Hormonal transitions are a natural part of a woman’s life, but the symptoms of perimenopause, menopause, and postmenopause can significantly impact daily well-being. For decades, women have sought solutions for symptoms like hot flashes, fatigue, mood swings, and sleep disturbances. And beyond symptom relief, hormone therapy plays a crucial role in long-term health, including the prevention of osteoporosis, heart disease, and cognitive decline.
Here’s what you need to know about BHRT, how it differs from conventional hormone therapy, and why it’s a can be an important part of a comprehensive wellness plan.
What Is BHRT?
BHRT uses hormones that are molecularly identical to those naturally produced in the body. These include bioidentical estradiol, progesterone, and testosterone, which are derived from plant sources and designed to match the body’s own hormones. Because of this precise match, bioidentical hormones are metabolized and utilized in a way that mimics the body’s natural hormone production.
How Is BHRT Different From the Hormones Used in the WHI Trials?
Many women remain hesitant about hormone therapy due to concerns raised by the Women’s Health Initiative (WHI) trials, which linked conventional hormone therapy to an increased risk of breast cancer, heart disease, and stroke. However, it’s essential to understand the key differences between the hormones used in those studies and BHRT.
- The WHI trials used synthetic progestins (medroxyprogesterone acetate) rather than bioidentical progesterone. Research now suggests that synthetic progestins (not bioidentical progesterone) are associated with an increased risk of breast cancer.
- The WHI trials primarily used oral conjugated equine estrogens (CEE), derived from pregnant mare’s urine, rather than bioidentical estradiol. Bioidentical estradiol, especially when delivered transdermally (via creams, patches, or gels), has been shown to have a better safety profile for cardiovascular health.
Since the WHI trials, further research has demonstrated that bioidentical hormones, when used appropriately and as part of a comprehensive health strategy, can be both safe and beneficial.

Benefits of BHRT
BHRT is not just about symptom relief; it is a proactive approach to long-term health. Research supports its role in:
- Bone Health: Estrogen plays a vital role in bone density. BHRT can reduce the risk of osteoporosis and fractures, which increase significantly post-menopause.
- Heart Health: Bioidentical estrogen may support cardiovascular function by improving lipid profiles and vascular health.
- Brain Health: Hormone therapy has been linked to a reduced risk of cognitive decline and dementia.
- Mood and Energy: Testosterone and progesterone play a role in mental clarity, mood stability, and energy levels, making BHRT an important tool for emotional well-being.
Of course, hormone therapy is not one-size-fits-all. BHRT should be tailored to the individual, and my approach is to start at a low to mid-range dose and adjusting based on response. It should be part of a comprehensive wellness plan that includes nutrition, lifestyle, and targeted supplementation – all of which I incorporate into my approach.
The Role of Compounding Pharmacies in BHRT
Many women benefit from customized BHRT formulations made by compounding pharmacies. Unlike mass-produced hormone medications, compounded BHRT allows for:
- Personalized dosing tailored to each woman’s unique needs.
- Alternative delivery methods (such as creams, lozenges, or sublingual drops) based on individual preferences, sensitivities and absorption
- Hormone combinations that address multiple imbalances at once.
I prefer to work with trusted compounding pharmacies that follow stringent quality standards, though I also collaborate with traditional pharmacies when insurance coverage is a priority for my patients.
A Balanced Approach to BHRT
While BHRT offers many benefits, it should always be administered with care, guided by lab testing, and monitored over time. Hormone balance is dynamic, and adjustments may be necessary as a woman’s needs change.
For over 25 years, I have helped women navigate perimenopause, menopause, and postmenopause using a comprehensive, research-driven, and integrative approach. I trained with leaders in naturopathic and functional medicine in women’s health and BHRT, and my practice is built on the foundation of empowering women with safe, effective, and personalized care.
If you’re considering BHRT or want to explore a comprehensive approach to hormonal health, I invite you to schedule a consultation. Together, we’ll create a plan that helps you feel balanced, vibrant, and at home in your body.